Amelogenin gene influence on enamel defects of cleft lip and palate patients

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Amelogenin gene influence on enamel defects of cleft lip and palate patients.

The aim of this study was to investigate the occurrence of mutations in the amelogenin gene (AMELX) in patients with cleft lip and palate (CLP) and enamel defects (ED). A total of 165 patients were divided into four groups: with CLP and ED (n=46), with CLP and without ED (n = 34), without CLP and with ED (n = 34), and without CLP or ED (n = 51). Genomic DNA was extracted from saliva followed by...

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Influence of lip closure on alveolar cleft width in patients with cleft lip and palate

BACKGROUND The influence of surgery on growth and stability after treatment in patients with cleft lip and palate are topics still under discussion. The aim of the present study was to investigate the influence of early lip closure on the width of the alveolar cleft using dental casts. METHODS A total of 44 clefts were investigated using plaster casts, 30 unilateral and 7 bilateral clefts. Al...

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Oral anatomical defects associated with cleft palate and cleft lip

Patients suffering from a cleft palate and/or cleft lip present evident anatomical defects in both formations. However, these developmental disorders are often accompanied by important disturbances in other anatomical structures of the mouth and adjacent tissues that may affect normal dental occlusion and, consequently, the basic functions of mastication and phonation. The objectives of the pre...

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Cleft Lip and Cleft Palate

Cleft lip (cheiloschisis) and cleft palate (palatoschisis) can occur individual or together. Individuals with CLP may experience problems with feeding, speaking, hearing and social integration that can be corrected to varying degrees by surgery, dental treatment, speech therapy and psychological intervention. In India over 35,000 babies per year are affected. This review signifies the etiologic...

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ژورنال

عنوان ژورنال: Brazilian Oral Research

سال: 2014

ISSN: 1807-3107,1806-8324

DOI: 10.1590/1807-3107bor-2014.vol28.0035